Unraveling Disparities In Breast Cancer
Why are black women more likely than white women to develop certain aggressive subtypes of breast cancer or to die from the disease? The National Cancer Institute has launched a collaborative research project to try to pinpoint genetic factors that underlie these and other disparities.
The Breast Cancer Genetic Study in African-Ancestry Populations is the largest study ever to investigate genetic and biological factors behind black womens risk of breast cancer. It wont enroll new patients, but will bring together researchers and data from a variety of venues, including the African-American Breast Cancer Consortium and the African-American Breast Cancer Epidemiology and Risk Consortium. Minority scientists from various institutions are playing an important role in the study, the NCI says.
The researchers will share biospecimens, data, and resources on 20,000 women involved in 18 previous studies. The genomes of those women will be compared with those of 20,000 black women who do not have breast cancer, as well as with white women who do. The project will investigate genetic variations associated with breast cancer risk in black women and gene expression in tumor samples to identify genetic pathways.
Cannabidiol For Fibromyalgia Pain
Cannabidiol is an active ingredient extracted from the flowers, leaves and stems of industrial hemp plants. These plants are specially selected to ensure high levels of CBD but low levels of the psychoactive substance, THC found in marijuana. CBD is mixed with olive oil, coconut oil or hemp seed oil to maximise its absorption.
Cannabidiol or CBD oil has direct effects on the brain to reduce pain perception, relieve anxiety, lift mood and promote refreshing REM sleep. It works by enhancing the effects of other brain chemicals, such as serotonin, and through effects on the brains own endocannabinoid systems. CBD does not produce a high and is not addictive.
CBD oil is antioxidant and has anti-inflammatory effects to improve pain and stiffness. It also has a direct analgesic effects on pain perception in the brain, is relaxing and promotes feelings of well-being. CBD oil also improves sleep quality by promoting deep and refreshing REM dream sleep.
See the best CBD oil products at Healthspan.co.uk , or .
What Causes Chronic Fatigue Syndrome
A person with CFS can often identify a severe infectious episode, of viral, bacterial, or parasitic nature prior to the onset of chronic fatigue. However, despite extensive research, the exact cause remains unclear, because several medical problems can cause CFS, including infection, hormonal imbalance, and immune system problems. A 2011 study from Norway found much support for the theory that CFS is a disorder of the immune system preceded in the majority of patients by an infection of some type.
Some suspect viruses thought to trigger CFS include Epstein-Barr, human herpesvirus 6, and mouse leukaemia viruses. In Australia, entero virus, retrovirus, Barmah Forest Virus, Ross River virus and other non-viral infections have been shown to trigger CFS.
Rather than recover fully after a few weeks of rest and treatment, CFS sufferers continue to experience multiple clinical problems for an extended period, even several years or decades.The immune system of a person with CFS is slightly impaired, but whether the immune impairment actually causes the disorder or is a consequence remains unclear.People with CFS often exhibit abnormal hormone function of the hypothalamic-pituitary-adrenal axis, a major regulatory component of the neuroendocrine system, which determines how a person reacts to stress and important bodily functions such as reproduction, immune system, digestion, energy storage and expenditure, moods, and emotions
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For Immune System Function
Bromelain
Bromelain has digestant activity and has anti-inflammatory, immunomodulatory, anti-diarrheal, anti-carcinogenic and wound-healing properties.
“The mechanism of the putative antiinflammatory activity is not well understood. It may be accounted for, in part, by activation of plasmin production from plasminogen and reduction of kinin, via inhibition of the conversion of kininogen to kinin.”
Bromelain also increases T-cell activation, and enhances antigen-independent binding to monocytes. It has been shown to help in chronic bronchitis and chronic sinusitis because it also thins mucous.
Contraindications: Avoid if allergic to pineapple.
Precautions: May cause blood-thinning activity in some people.
Adverse Reactions: Sometimes minor GI symptoms.
Interactions: Increases serum levels of amoxicillin and tetracycline. May enhance anticoagulant activity of warfarin and aspirin.Dosage: 500-2000 GDUs taken 1-3 times a day.
Magnesium
“Magnesium is an essential mineral in human nutrition with a wide range of biological functions. Magnesium is involved in over 300 metabolic reactions. It is necessary for every major biological process, including production of cellular energy and the synthesis of nucleic acids and proteins. It is also important for the electrical stability of cells, the maintenance of membrane integrity, muscle contraction, nerve conduction and the regulation of vascular tone, among other things.”
Adverse reactions: Usually none in doses of 350 mg a day or less.
How Do Supplements For Chronic Fatigue Syndrome Help
Chronic fatigue syndrome is a complex condition that can be difficult to treat. While there is no one-size-fits-all approach, many people find that supplements can help to ease their symptoms.
Supporting the systems affected by CFS can provide relief as the body heals. Support for energy function in the mitochondria, brain function, muscle soreness, fatigue, and sleep support are a few systems that supplementation can support.
Mitochondrial function, in particular, has been noted as an essential aspect of managing CFS.
It is important to note there is research on these supplements, and we will discuss the study in each section. However, supplements and vitamins are not researched as thoroughly as medications, so the evidence is typically not as strong.
Discuss your CFS with your healthcare provider and see if a supplement might make sense for you to try.
About our ratings:
We look at the research backing each supplement and reference the findings in our suggestions.
Quality
A high-quality supplement, herb, and vitamin will typically be a little more expensive because it uses high-quality ingredients. Supplements should be a supplement to your healthy lifestyle and diet and stay as clean and natural as food.
Lower quality vitamins and supplements typically have inferior quality ingredients and fillers that decrease the efficacy.
Price
Supplements can be expensive, but they dont have to be. We will rate the pricing based on the quality of ingredients and efficacy.
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How Is Cfs Treated
- No single treatment has shown strong or consistent success for CFS. The most important consideration is that treatment be customized to the individual and evaluated and administered on a case-by-case basis.
- While a wide range of drugs have been studied and used for CFS, none have provided consistently satisfactory results, and for many the side effects outweigh the benefits. However, stimulant drugs and drugs with antiviral and/or immunomodulating properties have been shown to improve symptoms of CFS.
- Mind-body therapies, like cognitive behavioral therapy and biofeedback, are important symptom-controlling interventions associated with overall functional improvement.
- Exercise-based therapies are a double-edged sword and need to be carefully tailored to individual energy budget and physical activity threshold to prevent debilitating malaise.
Lysine Or Theanine Supplements
The latest revelations show that there is a connection between Chronic Fatigue Syndrome and a weak immune system. Patients with CFS tend to have a weak immune system, which may also be a sign of the onset of an autoimmune disease. To avoid taking chances, you are advised to take lysine or theanine supplements to boost your immune function and alleviate the symptoms of chronic fatigue.
Get yourself treated for chronic fatigue syndrome by expert doctors. Click the button below to book your appointment.
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What Vitamins Are Good For Chronic Fatigue
Most dietary supplements used to treat chronic fatigue normally address nutritional deficiencies and other related symptoms. With this in mind, you should think about the symptoms that you have and find out what vitamins can help alleviate these specific symptoms.
The ideal vitamins for treating chronic fatigue syndrome include Vitamin B6, Vitamin B12, and Vitamin D3.
Vitamin B6 is found in foods like poultry, beans, oats, and bananas, and its role is to boost the immune system. Vitamin B12 alleviates stress and it is found in animal protein. Vitamin D3 is found in fatty fish and egg yolk and its role is to regulate insulin levels, boost the immune system, and absorb calcium to keep your bones healthy and strong.
Vitamin B3 And Vitamin B12
All of the B vitamins are important in mitochondrial health. All of them. Thats why taking a supplement of B-complex vitamins will form a solid foundation. But you will need additional support via vitamin B3 and vitamin B12.
Vitamin B3:
Vitamin B3 is more often known as niacin. If youve ever taken too much of this vitamin youll have experienced redness, or, flushing of your skin with an accompanying itch. This is known as a niacin flush. Fortunately, there are new forms of niacin that make for happy skin and mitochondria.
As far as energy production is concerned, the most important function of vitamin B3 is making your mitochondria more efficient so they can make more energy.
Dosing:
New forms of vitamin B3 known as nicotinamide riboside seem to be the most efficient at improving mitochondrial and ATP production. If youre unable to find nicotinamide riboside, opt for niacinamide but ensure its a slow-release formula. This will prevent any of the uncomfortable skin reactions.
Take 500-1500mg daily.
Vitamin B12:
Vitamin B12 is known as cobalamin. This is the form many supplements come in. But for those with chronic fatigue syndrome, youll want to take your vitamin B12 in its methylated form methylcobalamin.
Vegetarians and vegans are at increased risk of vitamin B12 deficiencies, so if you are on either a vegetarian or vegan diet, ensure you are supplementing B12 daily.
Dosing:
Bi-weekly or monthly B12 injections or 5000mcg sublingual on a daily basis.
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Conventional Medical Treatments Doctors Use To Treat Chronic Fatigue
People who receive an early diagnosis and early treatment enjoy better health outcomes. Support from family and friends, people at school and work, and health workers who understand the potential seriousness of CFS, can make a significant difference to recovery. Find a good doctor you trust a doctor who is sympathetic to CFS and knows how to treat the problem.
The treatment goal should be enhancement towards and preservation of an individuals best functional capacity. The lifestyle restrictions associated with CFS can lead to isolation, frustration, and in turn secondary depression. Low doses of an antidepressant drug can treat depression, improve sleep quality, and relieve pain.
No one treatment has been shown to cure CFS and so symptoms are treated as needed. The most effective treatment for CFA can be an energy-management strategy called pacing knowing when enough is enough and not overdoing mental or physical exertion.
A doctor will usually treat the most disruptive symptoms first, which usually includes:
- Fatigue and sleep problems
The most commonly used medications and supplements are:
Many people with CFS report an increased susceptibility to drug side effects, so any new medications should start with a small dose to assess tolerance. Start just one new treatment at a time to assess effectiveness. CFS symptoms reoccur so keep medications and supplement in case they are needed later on, just check the expiry date before reuse.
Treatments For Chronic Fatigue Syndrome
Since researchers do not yet fully understand the cause of chronic fatigue syndrome/myalgic encephalomyelitis and people with the illness can experience a wide variety of symptoms, multiple treatments exist. Treatments are aimed at managing and reducing the severity of CFS/ME symptoms, rather than at curing the illness.
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Build Peace And Relax
CFS can be debilitating both physically and mentally. Suffering from persistent exhaustion, reduced brain cognition, chronic muscle and joint pain, stress, and even guilt takes a toll on the body, and psyche.
Long-term stress control and relaxation must be a vital portion of any protocol used to overcome chronic fatigue syndrome. While seemingly impossible, its imperative that sufferers of CFS do their best to effectively manage stress, and rest.
The Power of Rest
Rest means more than just sleep. Dedicate one day per week when you dont have any responsibilities or commitments. Truly commit to a full day of rest. This gives your body and mind a much-needed respite helping to fight stress, anxiety and exhaustion. Its also important during the week, if you are having a particularly difficult day, to not overtax yourself.
While regular exercise supports wellness and helps to diminish stress, individuals with chronic fatigue syndrome need to exercise at a controlled intensity. High-intensity workouts can leave you drained for several days.
Exercise Therapy
Exercise therapy has been shown to help with fatigue, mental clarity and depression in patients with chronic fatigue syndrome. According to a study released in the European Journal of Clinical Investigation, individuals with CFS were recommended to perform aerobic activities, at the clinic twice per month, in combination with at-home exercises for roughly 5-15 minutes in duration, five days per week.
Sleep
How Many Vitamins For Tiredness And Fatigue Should You Take A Day
The number of vitamins for tiredness and fatigue you should take a day is sadly not a one answer question. This will vary from one vitamin to another and also factors in that the bodys need for each of the individual vitamins and minerals is massively various. While women require 18mg of iron a day and men require 8mg, the adult body only needs about 1.5 micrograms of vitamin B12 a day.
For reference, if we look closer at a few of the vitamins on this list and their recommended dosages from their available Holland & Barrett offerings, you can see how they differ.
Their Vitamin B12 tablets are advised to be taken at a dose of one to two tablets a day, preferably with meals and emphasises that the dose should not be exceeded.
The Vitamin C Timed Release caplets suggests taking a dosage of between one and four capsules a day with the same guidance in conjunction with meals. This mirrors the instructions provided for Holland & Barrett Biotin tablets, also.
The brands Active Iron capsules should only be taken at a dosage of one a day with no specific timing of consumption recommended.
Additionally, always be careful to read the ingredients list to ensure that youre familiar with what youre increasing your intake of.
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Try Heating And Cooling To See What Helps
Temperature sensitivity is another common symptom of ME/CFS. Its sometimes easy to overheat and difficult to cool back down. You can mitigate this symptom by using heating or cooling products. Try taking a warm or cool bath with Epsom salts before bed to optimize your temperature.
If your muscles are uncomfortably tight, you can use heat to soothe them. You can try using a heating pad, hot water bottle, or heated slippers. This will warm you up and relax your muscles at the same time.
Dealing with chronic fatigue syndrome can be frustrating, but there are many approaches you can take. Using supplements for CFS is another approach that has been shown to potentially improve your quality of life.
In addition to medication, you can also mitigate your symptoms by making healthy lifestyle changes.
Finding the right balance to ensure that your symptoms are under control is tricky. But its also essential to living a fulfilling life! You can do this.
What Are Causes And Risk Factors For Cfs
A specific cause of CFS has not been conclusively demonstrated, but several factors may correlate with CFS incidence:
- More common in women in early or middle adulthood
- Viruses such as human herpesvirus-6 and Epstein-Barr virus may play a role in the development of CFS
- Oxidative stress, excessive inflammation, mitochondrial dysfunction, and autoimmunity may also be involved
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Ashwagandha: The Ancient Stress Remedy
Ashwagandha has been used for over 3,000 years and has a wide variety of names. This herb grows in the Mediterranean and across the middle east, Africa, India, and Pakistan. It has been praised in traditional Indian medicine for its ability to help the body adapt to stress.
In a 2012 clinical trial, ashwagandha was shown to reduce blood levels of cortisol, which is known as the stress hormone. Participants in this study noted a significant reduction in the stress they experienced after 60 days, compared to the placebo group.
If it is stress that has you feeling drained, consider ashwagandha. As an added bonus, recent studies have also suggested that ashwagandha can improve endurance and muscle strength gains from exercise. Additionally, ashwagandha was shown to reduce food cravings and support body weight management, in a 2017 study.
Ready to start your personalized routine?
Supplement Options For Myalgic Encephalomyelitis/chronic Fatigue Syndrome
Myalgic encephalomyelitis/chronic fatigue syndrome is characterized by various symptoms such as fatigue, difficulty concentrating, trouble sleeping, and muscle aches. Some supplements may help reduce these symptoms. Supplements that may be beneficial include coenzyme Q10, nicotinamide adenine dinucleotide, ribose, magnesium, B vitamins, and vitamin D.
Because supplements have potential side effects and can interact with medications or other supplements, a medical professional should always be consulted before taking any new supplement.
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Talking With Your Doctor About Chronic Fatigue Syndrome
If you are experiencing fatigue on an ongoing basis despite getting adequate sleep, talk to your doctor. While you could be facing chronic fatigue syndrome, many illnesses ranging from obstructive sleep apnea to iron-deficiency anemia can cause fatigue. Your doctor will need to ask questions and order tests to determine what is causing fatigue in your personal situation. Preparing for your appointment can help it go more smoothly.
