What Novel And Emerging Therapies Appear Promising For Cfs
- DHEA replacement therapy in women who had CFS and low DHEA-S levels significantly improved fatigue, pain, memory, and sexual functioning.
- Repetitive transcranial magnetic stimulation , a non-invasive brain simulation technique, may be a useful therapeutic approach for helping manage symptoms of CFS.
For Immune System Function
Bromelain
Bromelain has digestant activity and has anti-inflammatory, immunomodulatory, anti-diarrheal, anti-carcinogenic and wound-healing properties.
“The mechanism of the putative antiinflammatory activity is not well understood. It may be accounted for, in part, by activation of plasmin production from plasminogen and reduction of kinin, via inhibition of the conversion of kininogen to kinin.”
Bromelain also increases T-cell activation, and enhances antigen-independent binding to monocytes. It has been shown to help in chronic bronchitis and chronic sinusitis because it also thins mucous.
Contraindications: Avoid if allergic to pineapple.
Precautions: May cause blood-thinning activity in some people.
Adverse Reactions: Sometimes minor GI symptoms.
Interactions: Increases serum levels of amoxicillin and tetracycline. May enhance anticoagulant activity of warfarin and aspirin.Dosage: 500-2000 GDUs taken 1-3 times a day.
Magnesium
“Magnesium is an essential mineral in human nutrition with a wide range of biological functions. Magnesium is involved in over 300 metabolic reactions. It is necessary for every major biological process, including production of cellular energy and the synthesis of nucleic acids and proteins. It is also important for the electrical stability of cells, the maintenance of membrane integrity, muscle contraction, nerve conduction and the regulation of vascular tone, among other things.”
Adverse reactions: Usually none in doses of 350 mg a day or less.
Best Supplements For Cfs That Will Actually Improve Your Symptoms
How Severe Is Your Lack Of Energy?TAKE THE QUIZ
Chronic fatigue syndrome, commonly referred to as myalgic encephalomyelitis/chronic fatigue syndrome , has no single standard treatment. There are, however, many ways to manage your symptoms and improve your quality of life. One way to do this is to try supplements for CFS.
In todays blog post, well discuss whether or not supplements are effective, along with the best supplements for CFS. Finally, well go over some other really good ways to improve your CFS symptoms. Lets get started!
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But What Vitamins And Minerals Are Necessary And Which Are Just Marketing Hype
Supplements get a bad rap. But they come by it honestly. All too often I see a new supplement guaranteed to increase your energy. But when you look at the ingredients list, youll typically see proprietary blend. The term proprietary blend is how manufacturers get around listing the actual amounts of vitamins and minerals in their supplements.
Proprietary blends are clever ways to make inferior supplements look legitimate. They are often accompanied by marketing campaigns that promise the world. But they hardly ever work the way they claim.
In the post, I do away with all the hype. Here, youll focus on exactly which supplements are needed in structuring a successful treatment plan to overcome chronic fatigue syndrome. The information presented here is based on scientific research, not marketing hype. You can rest assured that all of the supplements I list have been clinically tested for their efficacy in improving energy production and alleviating chronic fatigue syndrome.
Remember, not all supplements are created equal. Inexpensive brands found at drugstores often wont be able to be well absorbed by your body. Similarly, very high priced products may have an expensive marketing campaign to support and not offer a superior product. Purchase supplements with price points in the middle of the range. These brands are available online or in-store at health and wellness businesses.
Not All Energy Supplements For Fatigue Are Created Equal
But what vitamins and minerals are necessary? And which are just marketing hype?
In this post, I do away with all the hype. Here, I focus on exactly which are the best energy supplements for chronic fatigue syndrome. The information I present is based on scientific research, not marketing hype. All of the supplements I list are proven to improve energy production and alleviate chronic fatigue syndrome.
Keep in mind, your body often wont absorb inexpensive brands found at drugstores. Similarly, very high priced products may have an expensive marketing campaign to support and not offer a superior product. Purchase supplements with price points in the middle of the range. These brands are available online or in-store at health and wellness businesses.
To overcome chronic fatigue syndrome you need specific nutrients that target your fatigue at a cellular level.
You may find a supplement that promises to increase your energy, but when you look at the ingredients list, you see the words proprietary blend.
The term proprietary blend is how manufacturers get around listing the actual amounts of vitamins and minerals in their supplements.
Proprietary blends are clever ways to make inferior supplements look legitimate. They are often accompanied by marketing campaigns that promise the world. But they hardly ever work the way they claim.
Focusing on the performance of your mitochondria is how to know youre using the best energy supplements for chronic fatigue.
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Causes Of Chronic Fatigue Syndrome
We still know very little about chronic fatigue, and sadly, the cause is still unknown. While researchers continue to search for the root cause of CFS, there are preliminary findings that hormonal imbalances, poor immune system response, viral infections, chronic low blood pressure and nutritional deficiency are contributing factors.
In addition, research indicates that chronic fatigue syndrome may be linked to oxidative stress, Celiac disease, and food sensitivities or food allergies.
Most researchers believe that its a combination of factors that can vary from individual to individual. Viruses that can cause CFS include HHV-6, HTLV, Epstein-Barr, measles, coxsackie B, parovirus and cytomegalovirus.
Supplements For Chronic Fatigue Syndrome
Studies have suggested that coenzyme Q10 and nicotinamide adenine dinucleotide common antioxidant dietary supplements with known cardioprotective effectsmight relieve symptoms of chronic fatigue syndrome . Both supplements have been shown to significantly reduce fatigue levels and other symptoms associated with chronic diseases, such as fibromyalgia. Studies of their utility in treating CFS, however, have been very small with inconsistent conclusions, say researchers.
Because research has shown that a mitochondrial failure reduces the rate of adenosine-5-triphosphate synthesis, the central agent of energy production in CFS, and because CoQ10 and NADH increase cellular ATP production via mitochondrial oxidative phosphorylation, the researchers decided to conduct a proof-of-concept study to assess the effect of supplementation on heart rate, with secondary measures of fatigue, pain, and sleep.
In the eight-week study, 80 participants received CoQ10 200 mg once daily plus NADH 20 mg once daily or placebo . Heart rate was measured at baseline and at the end of the run-in period. Fatigue, pain, and sleep were evaluated at baseline, then again at four and eight weeks using participants self-report questionnaires.
The supplementation was safe and well tolerated, the researchers say, and could be added to conventional CFS therapy.
Source: Clinical Nutrition, August 2016
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Avoid Smoking And Chemical Exposures
People with CFS should avoid, as much as possible, exposure to tobacco smoke, toxic chemicals, and pollutants. Smoke contains many toxicants, including carbon monoxide and nicotine, which alter the function of the nervous system and may increase risk of chronic pain.170,171 Exposure to cigarette smoke, even secondhand, is pro-inflammatory and suppresses or disorders immune response.172 A large multi-center prospective study of 9,209 non-demented patients found higher cigaretteexposure correlated with significantly higher rates of cognitive decline.173 Other studies have linked tobacco smoke exposure withgreater symptom burden in CFS or related conditions .174,175
Exposure to toxic compounds has been associated with CFS.176,177 Some individuals with reported chemical sensitivities also have severe chronic fatigue. In some cases, CFS symptoms have resolved in chemically sensitive individuals when they reduced or eliminated their toxicant exposure.178
If possible, those with CFS should also live and work in well-ventilated buildings. Indoor levels of pollutants such as solvents, pesticides, and dust are generally higher in buildings with poor ventilation. In a study of 100 large office buildings, office workers experiencing fatigue or difficulty concentrating were less likely to work in well-ventilated buildings or buildings with well-maintained ventilation systems compared with less well-ventilated or well-maintained buildings.181
What Is Chronic Fatigue Syndrome
Chronic fatigue syndrome is a medical disorder that causes exhaustion and a lack of energy over time. It is not the same as being weary or exhausted from hard work or exercise, but persons who suffer from it may experience symptoms that are comparable.
Chronic tiredness patients frequently struggle to complete daily duties and may even struggle with simple tasks such as sitting upright or feeding themselves. For someone with chronic tiredness, activities that were formerly simple, like going out with friends or working a full-time job, and raising a family, can become burdensome and difficult.
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What Is Chronic Fatigue
This condition is best known by medical professionals as Chronic Fatigue Syndrome . Its a disorder that can be characterized by the feeling of extreme tiredness with no feeling of refreshment after sleep.
Imagine going to bed at night only to wake up feeling as if you didnt go to bed at all. Doesnt sound like sweet dreams now, does it?
Plus, the symptoms and signs only worsen if you take part in strenuous physical or mental activities, and they dont improve after rest and relaxation either. Its a slippery, downhill slope!
Vitamin B12 And Folic Acid
Researchers have been exploring whether vitamin B12 injection or other means of supplementation, along with folic acid, can relieve CFS symptoms.
There is a biochemical theory as to how this may be of benefit: People with CFS show reduced methylation which plays a role in gene expression as well as regulation of many of the bodys systems, including detoxification, cardiovascular and the neurologic system. Vitamin B12 and folic acid both promote healthy methylation pathways.
A study of B12 injections in addition to oral folic acid supplementation found that some subjects with CFS responded well, while others had only a mild response. A better response was associated with more frequent injections, lack of use of opioids, and a certain genetic phenotype.
Another study looked at using B12 nasal drops as an alternative to injections in subjects with CFS. This study also found good response in two-thirds of the participants. The researchers demonstrated that those who had a better response had a higher blood level of B12 and were more physically active .
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For Mitochondrial Energy Production
Acetyl-L-Carnitine
Acetyl-L-carnitine may have neuroprotective, cytoprotective, antioxidant and anti-apoptoticactivity.
There is speculation that acetyl-L-carnitine crosses the blood/brain barrier better than L-carnitine.
There are some studies backing up each of the activities mentioned. Peripheral nerve function has improved in diabetes.
Mitochondrial membrane potential improves with acetyl-L-carnitine, which improves the functioning of mitochondria.
Contraindication: None known.
Precaution: People with seizure disorders should only use this under medical supervision.
Adverse Reactions: Rarely, mild gastrointestinal symptoms such as nausea, vomiting, abdominal cramps and diarrhea.
Interactions: Therapy with nucleoside analogues didanosine, zalcitabine and stavudine, and with valproic acid and the pivalic acid-containing antibiotics may lead to secondary L-carnitine deficiency.
Dosage: 500-2000 mg daily in divided doses.
Alpha-Lipoic Acid
“Most of the metabolic reactions in which alpha lipoic acid participates occur in mitochondria. These include the oxidation of pyruvic acid by the pyruvate dehydrogenase enzyme complex.”
Alpha-lipoic acid and its metabolite DHLA scavenge a wide range of reactive oxygen species including hydroxyl radicals, the nitric oxide radical, peroxynitrite, and hydrogen peroxide. Alpha lipoic acid is approved for treatment of diabetic neuropathy in Germany. There is some evidence it may be useful in treating other aspects of diabetes as well.
NADH
Chapter : What Exactly Is Chronic Fatigue Syndrome
It is a condition where the person feels extreme tiredness and lack of refreshment after sleep. Can you imagine going to sleep only to feel tired and weary? You can imagine how terrible tiring that must be. You do not wake up feeling fresh and ready for the day. Additionally, the symptoms get worse when you exert yourself physically or mentally.
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How Supplements Can Help Improve Your Quality Of Life:
According to the National Institutes of Health is an intricate disorder described by extreme fatigue that cant be illuminated by any fundamental medical disorder. CFS can cause a wide range of symptoms, including difficulty concentrating, insomnia, and an overall feeling of malaise. While there is no cure for CFS, there are treatments that can help improve your quality of life. One such treatment is taking supplements.
There are a variety of supplements that have been shown to be helpful for people with CFS. For example, omega-3 fatty acids supplements can help reduce inflammation and pain. Coenzyme Q10 supplements can help improve energy levels and cognitive function. And magnesium supplements can help relieve muscle pain and cramps.
Taking a daily multivitamin is also recommended, as people with CFS tend to be deficient in a variety of vitamins and minerals. If youre considering taking any kind of supplement, its important to speak with your doctor first to make sure its safe for you and wont interact with any medications youre taking. But for many people with CFS, taking supplements can be an effective way to help improve their quality of life.
Hum Nutrition Uber Energy
Image courtesy Hum Nutrition
L-Tyrosine is known to increase focus and concentration, making it the perfect base for these Uber Energy capsules. These capsules are designed for busy people who want to make the most of their time and get things done. The adaptogens in these capsules help keep you focused, awake and stress-free so that you can power through your never-ending to-do list.
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The Mitochondrial Enhancers Pt I
In Mitochondria and the Future of Medicine, Lee Know, a licensed naturopathic doctor in Canada, has written an engagingly written overview of the field. It will provide the basis for this overview. Know, though, warns that hes by no means providing an exhaustive list of mitochondrial enhancers. This, then, is a basic overview of the major ones.
Adaptogenic Herbs The May Improve Chronic Fatigue
Several medicinal plants, known as adaptogens, have shown a non-specific ability to enhance the bodyâs overall resistance to mental and physical stress. Although the precise mechanisms are unclear, there is evidence that they may influence the HPA axis and several biochemical pathways involved in the bodyâs stress response.288
Adaptogenic herbs are of particular interest in CFS due to their reputation for boosting energy as well as their possible effects on the HPA axis and on supporting healthy immune system function. Some adaptogens considered promising for CFS include:
Additional information on adaptogens can be found in the Stress Management protocol.
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Super Fuel Natural Energy + Vitamin Drink
Image courtesy Super Fuel
If you’re looking for a healthier alternative to typical energy drinks, look no further! Our drink is fortified with plant-based caffeine, vitamins, minerals, nootropics, electrolytes, and antioxidants. It’s perfect for pre-workout or post-workout recovery, study sessions or work days when you need an extra boost of energy.
Chronic Fatigue Syndrome Symptoms
While the term chronic fatigue is fairly descriptive of this crippling illness, it doesnt tell the entire story. Chronic fatigue often starts suddenly, with flu-like symptoms. But unlike the flu, it can last a lifetime.
In addition to the profound fatigue experienced, other serious symptoms often accompany CFS, such as:
- joint pain that moves from one spot to another
- digestive disorders like irritable bowel syndrome .
Sufferers of chronic fatigue syndrome also experience significant alterations in levels of irritability, mood swings, panic attacks, anxiety and depression. According to a study published in Family Practice, 36 percent of individuals with CFS were clinically depressed and 22 percent had seriously considered suicide in the past year.
Simply, the emotional and mental side effects of CFS cannot be overlooked, and treatment must include the mind, body and spirit.
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Supplements Needed For Chronic Fatigue Syndrome
If youve read any of my previous posts, youre well aware that the root cause of chronic fatigue syndrome is mitochondrial dysfunction. Therefore, the supplements you take should be aimed at improving mitochondrial function. Below, I list the best researched-based supplements for chronic fatigue syndrome.
Food Intolerances And Chronic Fatigue Syndrome
CFS is linked to the immune system dysfunction, and this could explain why some sufferers believe certain foods worsen their symptoms.
The best way to identify whether a person is intolerant to a specific food or not, is to follow a food elimination or exclusion diet. The former involves removing suspected foods from the diet to see if symptoms improve, and the latter involves reverting to a very basic diet for a period of time before gradually reintroducing additional foods one at a time, to identify problem foods.
Elimination and exclusion diets could involve removing essential nutrients from the diet and so adequate supervision by a nutritional medicine specialist is recommended.
Another good place to start when indentifying food sensitivities is to keep a food diary of what you eat and when you experience the worsening of symptoms. This could help you to spot any patterns.
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Gaia Herbs Rhodiola Rosea Vegan Liquid Capsules 60 Count
5.0 – a holistic approach to chronic fatigue
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5.0 – YOU HAVE TO TAKE ENOUGH!!!!
This product has been the ONLY relief I have ever experienced for my chronic fatigue. I’ve tried many supplements, spent thousands of dollars for over 5 years. I started taking this supplement but not getting really any benefit. I realised a lot of companies offer higher strength versions with some being 500mg per capsule. This one only offers 120mg. I now take 4 capsules twice daily and the benefits are AMAZING!! I still have my ups and downs with my fatigue but I can now count on this product to give me hours of relief each time I take it! 8 highly suggest you purchase this for chronic fatigue and take the minimum effective dose! If one works for you take one, if you need to take 3 twice a day then do it!
5.0 – Powerful product
This product is so powerfully effective that I’m still trying to figure out exactly how much to use so that I don’t overdo it. I have Chronic Fatigue Syndrome, and in the over 30 years I’ve had it, this is the only product that actually does anything. It doesn’t remove the problem, but offers real support. Finally.
5.0 – Relief for Fatigue
